Do you often encounter cases where antihistamines alone are insufficient in controlling urticaria, leading to consideration of systemic corticosteroid therapy?
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This Indian study demonstrated telmisartan to be efficacious and tolerable for BP control in Indian hypertension patients when used as monotherapy or in combination therapy. The benefits of telmisartan were independent of age, duration, and stages of hypertension.
17 Apr, 24 J Allergy Clin Immu...
A study weighed efficacy vs. risks of systemic corticosteroids in treating acute urticaria & chronic urticaria flares. While corticosteroids demonstrated efficacy in improving urticaria control, their benefits depended on antihistamine responsiveness, showing improved results in cases where antihistamines alone did not suffice. However, systemic corticosteroids also increased the odds of adverse effects (OR, 2.76).
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17 Apr, 24EBioMedicine.
Research involving over 64,000 prurigo nodularis (PN) patients highlighted an increased risk for various acute cardiac events, such as heart failure and MI, alongside higher mortality rates. Chronic vascular and structural heart diseases such as peripheral arterial disease, chronic ischemic heart disease, and valvular disorders were also more prevalent following PN diagnosis, particularly among female patients.
18 Apr, 24BMJ Open Diabetes Re...
- In T1DM patients, 8 metabolites had a significant link with diabetic retinopathy, diabetic kidney disease & distal symmetric polyneuropathy, & 6 of them increased the microvascular burden severity
- Higher levels of 3,4-dihydroxybutanoic acid (DHBA), 2,4-DHBA, ribonic acid, glycine, & ribitol were associated with microvascular events
- These metabolites may improve risk assessment for diabetes complications
18 Apr, 24Clin. Infect. Dis.
- Wearing gloves reduced the risk for overall adverse events related to insertion compared to no gloves (aRR: 0.52)
- Catheter removal based on defined schedules resulted in a lower phlebitis/thrombophlebitis incidence (RR: 0.74) compared to clinically indicated removal in adults
- In neonates, chlorhexidine reduced the phlebitis score compared to non-chlorhexidine-containing disinfection (0.14 vs. 0.68, p = 0.003)
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