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26 Mar, 24
This Indian study demonstrated telmisartan to be efficacious and tolerable for BP control in Indian hypertension patients when used as monotherapy or in combination therapy. The benefits of telmisartan were independent of age, duration, and stages of hypertension.
17 Apr, 24EBioMedicine.
Research involving over 64,000 prurigo nodularis (PN) patients highlighted an increased risk for various acute cardiac events, such as heart failure and MI, alongside higher mortality rates. Chronic vascular and structural heart diseases such as peripheral arterial disease, chronic ischemic heart disease, and valvular disorders were also more prevalent following PN diagnosis, particularly among female patients.
17 Apr, 24JAMA Dermatol.
Erenumab, a monoclonal antibody targeting the calcitonin gene-related peptide (CGRP) receptor, has shown potential in treating individuals with rosacea-associated erythema and flushing. Administered every 4 weeks for 12 weeks, erenumab significantly decreased days with flushing and erythema compared to baseline. Adverse events were mostly mild and transient, with constipation being the most common.
18 Apr, 24BMJ Open Diabetes Re...
- In T1DM patients, 8 metabolites had a significant link with diabetic retinopathy, diabetic kidney disease & distal symmetric polyneuropathy, & 6 of them increased the microvascular burden severity
- Higher levels of 3,4-dihydroxybutanoic acid (DHBA), 2,4-DHBA, ribonic acid, glycine, & ribitol were associated with microvascular events
- These metabolites may improve risk assessment for diabetes complications
18 Apr, 24Clin. Infect. Dis.
- Wearing gloves reduced the risk for overall adverse events related to insertion compared to no gloves (aRR: 0.52)
- Catheter removal based on defined schedules resulted in a lower phlebitis/thrombophlebitis incidence (RR: 0.74) compared to clinically indicated removal in adults
- In neonates, chlorhexidine reduced the phlebitis score compared to non-chlorhexidine-containing disinfection (0.14 vs. 0.68, p = 0.003)
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