Medical News

Combination Therapy with Vancomycin and Beta Lactams Exhibits Superior Efficacy in Methicillin Resistant Staphylococcus aureus Infections

The synergy between vancomycin and beta-lactams against vancomycin-susceptible Staphylococcus aureus (VSSA), vancomycin-intermediate S. aureus (VISA...

13 Jun, 2018

 
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Variations in Pharmacokinetics of Single Dose Intravenous Posaconazole in Critically Ill Patients

The pharmacokinetics (PK) of a single dose of 300 mg intravenous (IV) posaconazole in critically ill patients were different than the PK in healthy...

11 Jun, 2018

 
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Procalcitonin Values Vary with the Type of Pathogen and Foci of Infection in Patients with Bacteremia

Secondary analysis of a randomized trial assessed whether serum procalcitonin (PCT) concentrations could be a predictor of gram-negative bacteremia...

08 Jun, 2018

 
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Tapering Vasopressors – Impact on Incidence of Hypotension in Patients with Septic Shock

A recent randomized study assessed the impact of tapering vasopressors on the incidence of hypotension in patients on concomitant norepinephrine (NE...

06 Jun, 2018

 
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Key Trials

GLIMP Study: Worldwide Prevalence and Risk Factors for MRSA Pneumonia

The Global Initiative for MRSA Pneumonia (GLIMP) study, is an international, multicenter study aimed to determine the point prevalence and specific...

BLISS Study: Continuous Administration of Beta-lactams Associated with Higher Clinical Cure Rates and Better PK/PD Target Attainment Compared to Intermittent Bolus Dosing

Beta-lactam Infusion in Severe Sepsis (BLISS) study is a prospective, two-centre, open labelled, randomized controlled trial of continuous infusion...

ZEPHyR Study: Linezolid Superior to Vancomycin in Treatment of MRSA Nosocomial Pneumonia

ZEPHyR (linezolid in the treatment of subjects with nosocomial pneumonia proven to be due to methicillin-resistant Staphylococcus aureus) is a...

Prevalence of Methicillin-Resistant S. aureus Infection among Patients in the Emergency Department

In this study, MRSA was identified as the leading cause of skin and soft tissue infections among patients in the emergency department.

Slide Library

Cefuroxime (Novacef)

Cefuroxime is a second-generation cephalosporin antibiotic. It is a broad-spectrum antibacterial agent with a favorable pharmacokinetic profile....

 
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Management of Mucormycosis in ENT Practice

Mucormycosis are the group of invasive infection caused by filamentous fungi of the Mucoraceae family. This slide set enumerates prevalence,...

 
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Antifungal Therapy in Immunocompromised Patients

Early initiation of antifungal therapy is a major contributor to enhanced survival rate. This set of slides highlights incidence and risk factors of...

 
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Disseminated Tuberculosis with ARDS

Disseminated TB results from widespread blood borne dissemination of TB bacilli. This presentation includes causes and risk factors of disseminated...

 
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Our Publications

Clarithromycin: An Emerging Treatment Recourse in Lower Respiratory Tract Infections

Parenteral macrolide therapy is needed for patients with moderate to severe CAP/AECB. This booklet gives an overview of the efficacy and safety of...

MRSA: The Clinician’s Challenge

The article summarizes the Indian epidemiological data for MRSA infections, along with treatment of MRSA infections and infection control measures.

Phosome IV (Liposomal Amphotericin B) Monograph

Amphotericin B deoxycholate has a broad antifungal activity, and today it is the best antifungal available against most systemic fungal infections,...

Liposome: The Magic Bullet

This article briefs out the structural aspects, advantages and application of liposomes and elaborates on liposomal amphotericin B as an antifungal...

Clinical Tools

Management of Clostridium Difficile Associated Dairrhoea (...

The algorithm for the treatment of Clostridium difficile associated diarrhea is presented here.

 
Antimicrobial Spectrum Reckoner

This aid is a ready reckoner of antibiotics and anti-fungals against a spectrum of gram positive and negative microbes and resistant pathogens.  

 
Candida Score

This aid is a ready reckoner scoring system for early antifungal treatment in non-neutropenic critically ill patients.

 
ICU Scoring Systems

The 11 scoring systems frequently required and widely used to assess the severity of critically ill patients in the ICUs are listed here.

 

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Do you perceive any clinical benefits of neurotrophic agent in the management of acute brain injury?
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