ACNEDAP Gel (Dapsone)
Table of Content
Acne vulgaris is a common skin disease with the onset in adolescence. It is characterized by inflammatory and non-inflammatory lesions.
Dapsone, a synthetic sulfone has been available for over 60 years and has been used to treat myriad of cutaneous disorders. Prior to the general acceptance of isotretinoin, oral dapsone had been reported to be effective in the treatment of nodulocystic acne. However, the potential for systemic toxicity prevented with widespread use in the treatment of acne. Hence, dapsone in gel formulation was developed and was approved by the US FDA in 2005 for use in the treatment of acne vulgaris.
Dapsone has both antibacterial and anti-inflammatory properties. Multiple pharmacokinetic and clinical studies showed that dapsone gel 5% is effective, safe and well-tolerated in the treatment of acne vulgaris. Dapsone gel 5% offers the advantage of delivering clinically effective doses with minimal systemic exposure.
ACNEDAP gel contains dapsone 5%. It is indicated for the topical treatment of acne vulgaris. ACNEDAP gel should be applied as a thin layer to the affected areas twice daily for 12 weeks. It is not recommended for use in patients below 12 years of age.
ACNEDAP gel is available in a tube of 15 g.