All You Need to Know About Erlotinib

Table of Content

What You Should Know About NSCLC?

Lung cancer occurs when cells in the lung grow abnormally out of control and form tumors

Lung cancer includes two main types

  • Non-small cell lung cancer (NSCLC)
  • Small cell lung cancer

80% - 85% of lung cancers are NSCLC

What is Erlotinib?

Used to treat NSCLC by preventing the activity of EGFR, a protein involved in the growth and spread of cancer cells.

Indication

  • EGFR positive metastatic NSCLC
  • Metastatic pancreatic cancer

Before Taking Erlotinib

Inform Your Doctor About Medications You are Taking

History of eye inflammation

Do not take Erlotinib, If you are allergic to Erlotinib.

All About Your Medical Conditions, Including

 Liver disease

Not recommended in severe liver disease

 Kidney disease

Not recommended in severe kidney disease

Hypersensitivity

If you have an intolerance to some sugars, such as lactose.

Other Conditions

  • Smoking

It is advised to stop smoking if you are treated with Erlotinib

  • Driving and using machines
  • Children and adolescents

Erlotinib is not recommended for children and adolescents.

  • Pregnancy and breast-feeding

Do not breast-feed if you are being treated with Erlotinib, and for at least 2 weeks after taking the last tablet.

  •  Erlotinib with food and drink

Do not take Erlotinib with food

During Erlotinib Therapy

Inform Your Doctor If You Experience

  •  Sudden difficulty in breathing with cough
  •  Fever
  • Persistent diarrhea and loss of appetite
  • Nausea or Vomiting
  • Severe pain in the abdomen
  • Redness and pain in the eye
  • Severe blistering or peeling of skin

Taking Erlotinib

Always take erlotinib exactly as directed by your doctor

At least 1 hour before or 2 hours after food.

The usual dose is: 

  • For NSCLC

1 Tablet - 150 mg OD

  • For Pancreatic Cancer

1 Tablet- 100 mg OD

  • If you take more Erlotinib than needed, contact your doctor immediately.
  • If you miss one or more doses contact your doctor as soon as possible.
  • Do not take a double dose to make up for a missed dose.
  • Its important to take daily dose as prescribe by the Doctor

What Are the Possible Side Effects of Erlotinib?

Like all medicines, this can also cause some side effects in few people. Contact your doctor as soon as possible if you have any of the below side effects.

  • Rash which worsens in sun exposed areas
  • Altered skin sensation or numbness
  • Decreased weight
  • Loss of appetite
  • Depression and Headache
  • Severe or persistent diarrheoa
  • Difficulty in breathing
  • Nausea
  • Mouth irritation
  • Stomach pain indigestion and flatulence
  •  Itching and dry skin
  • Loss of hair

How to Store Erlotinib?

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date written on the blister and carton.

To report any side-effects, write to drugsafety@cipla.com . You can also report side effects directly via the national pharmacovigilance program of India by calling on 1800 180 3024 or you can report to Cipla Ltd on 1800 267 7779. By reporting side-effects, you can help provide more information on the safety of this product.

Abbreviations

NSCLC: Non -Small Cell Lung Cancer; EGFR: Epidermal growth factor receptor;

OD: Once daily.

References

1. Non-Small Cell Lung Cancer Treatment. httpps://www.cancer.gov/types/ lung/hp/non-small-cell-lung-treatment-pdq. last accessed 24th Mar 2021

2. What is lung cancer? https://www.cancer.org/cancer/lung-cancer/about/ what-is.html last accessed 24th Mar 2021.

3. Approved prescribing information of Erlotinib.

Rating: 
0
Your rating: None