Compositional and Drug-resistance Profiling of Pathogens in Patients with Severe Acute Pancreatitis: A Retrospective Study

BMC Gastroenterol

The bacterial spectrum and drug resistance characteristics of SAP patients provide a certain reference for the empirical use of antibiotics and the regulation of intestinal microecological treatments. Our study found that gram-negative bacteria were the most common pathogens in SAP infection, and the proportion of gram-positive bacteria increased notably. Besides, more kinds of antibiotics and ICU hospitalization are risk factors for MDR bacterial infections.