CYTOCARB Injection (Carboplatin)

Table of Content


CYTOCARB 150/450 Injection
Each ml contains:
Carboplatin USP .......................10 mg
Water for injection I.P. ...............q.s.


  • Advanced Ovarian Carcinoma
  • Small cell lung carcinoma

Dosage and Administration

Calvert formula shown below may be used to determine dosage
Dose (mg) = target AUC (mg/ml x min) x

Note: With the Calvert formula, the total dose of carboplatin is calculated in mg, not mg/m2.


Carboplatin is contra-indicated in patients with:

  • Hypersensitivity to the active substance or to other platinum containing compounds
  • Breast feeding
  • Severe myelosuppression
  • Bleeding tumours
  • Pre-existing severe renal impairment (with creatinine clearance of ? 20 ml per minute).

The Most Common Adverse Reactions

Myelosuppression, subclinical

decrease in hearing acuity, nausea , diarrhoea , alopecia, constipation , mucositis, renal toxicity , decreases in serum electrolytes (sodium, magnesium, potassium and calcium), hyperuricaemia , peripheral neuropathies, abnormalities of liver function tests etc.


Store in a cool dry place. Do not refrigerate.

Packaging Information

CYTOCARB 150/450 Injection: Single dose vials of 15 ml and 45 ml