The Impact of Apical Periodontitis, Non-surgical Root Canal Retreatment and Periapical Surgery on Serum Inflammatory Biomarkers

Int. Endod. J.

Both symptomatic and asymptomatic AP can contribute to increased levels of molecular markers of inflammation. A further transient inflammatory markers rise after root canal retreatment and apical surgery was demonstrated. Successful endodontic treatment and periapical surgery result in a long-term reduction of inflammatory marker levels.