The negative effect of progesterone levels on the day of hCG administration (Phcg) on live-birth rate (LBR) is not restricted to values above 1.5 ng/ml in IVF/ICSI cycles


Conclusion : Our model provides evidence of an important negative impact of P hcg at both lower and higher values, independent of oocytes number, thus defining a proper range for Fresh Embryo Transfer or Freeze-All strategy. In poor responses, PE may be neglected, thus avoiding unnecessary cancellations or embryo freezing. Conversely, in the higher responses, the negative effect of PE appears more pronounced, suggesting that freeze-all policy should be applied more widely.