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    21 Aug, 2018
    Heart failure (HF) patients with end-stage renal disease (ESRD), have substantially increased in-hospital mortality, reported a recent study. In fact, this increase was nearly two-fold (86%) for systolic HF patients, though diastolic HF patients also had a modest (11%) increase in in-hospital mortality. All HF patients with ESRD also had substantial increases in hospital costs, intensive care... Read more
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    21 Aug, 2018
    The incidence of group B streptococcus (GBS) infections in children has diminished, yet; the risk of poor health outcomes associated with GBS has remained elevated in children particularly during the first 5 years, stated a recent study. Furthermore, the study revealed a continued increased risk of death and chronic conditions requiring hospitalisations (e.g., as cerebral palsy and epilepsy)... Read more
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    21 Aug, 2018
    A recent study determined the factors and outcomes associated with candidemia caused by non- albicans Candida (NAC) spp versus Candida albicans in children. The study identified non-albicans Candida (NAC) as the predominant species in children with candidemia. Increased risk of candidemia caused by NAC species was associated with prolonged use of a central venous catheter, noted researchers. The... Read more
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    20 Aug, 2018
    A novel study recently ascertained the intraocular pressure (IOP)-reducing effect of latanoprost at all untreated IOP levels in newly detected glaucoma patients. According to the findings, the IOP reducing effect of latanoprost was proportional to the untreated IOP at all levels exceeding16 mm Hg. In fact the IOP reducing impact was relatively better at higher untreated IOP levels. These findings... Read more
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    20 Aug, 2018
    A recent study investigating the characteristics of a unique form of rhinosinusitis, Sinus Fungal Ball, demonstrated that these patients experienced robust immune responses, allowing recruitment and activation of macrophages and neutrophils. This unique form of rhinosinusitis was predominantly found in females, older patients, patients with immunodeficiency and the presentation was mostly... Read more
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    20 Aug, 2018
    A recent multicentric study established the efficacy and safety of rifaximin therapy in nonalcoholic fatty liver disease (NAFLD).  The results of the study demonstrated that rifaximin therapy reduced serum endotoxin and improved insulin resistance, proinflammatory cytokines, cytokeratin-18 (CK-18), and NAFLD-liver fat score.   Factors such as increased insulin resistance, upregulation... Read more
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    20 Aug, 2018
    Medial unicompartmental knee arthroplasty (UKA) has been a successful option for treatment of arthritis in patients with the healthy lateral compartment. A recent study compared the progression of radiographically evident osteoarthritis in unoperated compartments during five years after lateral and medial UKA. The results showed an increase (i.e worsening) in all mean disease grades for the... Read more
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    20 Aug, 2018
    Type-2 diabetes mellitus (T2DM) patients with five risk-factor variables (elevated glycated hemoglobin level [HbA1c], elevated low-density lipoprotein cholesterol [LDL-C] level, albuminuria, smoking, and elevated blood pressure) within the target range had little or no excess risk of death, myocardial infarction (MI), or stroke as compared to the general population, reported a recent large-scale... Read more
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    20 Aug, 2018
    The Definitive Intervention in New Onset Rheumatoid Arthritis (DINORA) study investigated the effects of immediate induction therapy with the anti-tumour necrosis factor (TNF) α antibody infliximab (IFX) plus methotrexate (MTX) and compared with MTX alone and with placebo (PL) in patients with very early inflammatory arthritis. Results of this recent study reported a long-term benefit associated... Read more
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    17 Aug, 2018
    Patients undergoing simultaneous colorectal/liver resections are at high risk of surgical site infections (SSIs). A recent study evaluated the effects of the SSI reduction intervention in patients undergoing combined colorectal/liver resection at Memorial Sloan Kettering Cancer Center, USA. The results showed that implementation of multidisciplinary care bundle in patients undergoing synchronous... Read more
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    17 Aug, 2018
    A recent study compared the long-term effectiveness of fluticasone propionate administered by metered dose inhalers (MDI) with non-valved spacers (NVS) versus MDI with valve-holding chambers (VHC) in infants with recurrent wheezing and at risk of developing asthma. It was noted that fluticasone propionate administered by MDI without valves was less effective than such treatment by MDI with valves... Read more
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    17 Aug, 2018
    A recent study evaluated the effects of local anesthetics soaked nasal packs on pain and bleeding following septoplasty. The application of articaine plus adrenaline soaked nasal packs after septoplasty was associated with better analgesia and less hemorrhage on the first postoperative day and was devoid of any complication. The authors of the study suggested the use of topical articaine plus... Read more
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    17 Aug, 2018
    A recent meta-analysis evaluated the efficacy of Extracorporeal shock-wave therapy (ESWT) for knee soft tissue disorders (KSTDs) and compared it with the effectiveness of different shock-wave types, energy levels, and intervention durations.  The study showed that ESWT significantly increases treatment success rate (TSR), reduces pain, and improves functional recovery in patients with KSTDs... Read more
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    16 Aug, 2018
    A recent prospective study investigated the effect of screen-and-treat strategy on the development of surgical site infections (SSI) in patients undergoing aortoiliac surgery. Pre-operative nasal screening and eradication therapy with mupirocin and chlorhexidine in this study population resulted in decrease in the incidence of Staphylococcus aureus (S. aureus) SSIs and its complication after... Read more
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    14 Aug, 2018
    Patisiran infusion is the first drug to be approved by the U.S. Food and Drug Administration (FDA) for the treatment of adults with peripheral nerve disease (polyneuropathy) caused by hereditary transthyretin-mediated amyloidosis (hATTR). Patisiran is the first member from the novel class of drugs; the small interfering ribonucleic acid (siRNA) treatment, to have received such an approval.... Read more