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    12 Nov, 2019
    A recent study reaffirmed that diabetes is a continuous spectrum of type-1 diabetes mellitus (T1DM), latent autoimmune diabetes in adults-1(LADA1), LADA2 and type-2 diabetes mellitus (T2DM). The study further demonstrated that patients with LADA and T1DM had impaired insulin sensitivity and beta (β)-cell function and patients with LADA and T2DM exhibited insulin resistance (IR). The findings may... Read more
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    12 Nov, 2019
    A recent study that reported a high prevalence of diabetic nephropathy (DN) in T2DM patients manifesting heavy proteinuria, revealed that longer duration of T2DM (≥7.5 years), presence of retinopathy, higher systolic blood pressure (SBP), and higher serum albumin were independently associated with DN in such patients. Researchers recommended renal biopsy to be reserved for T2DM patients with... Read more
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    12 Nov, 2019
    The target fasting blood glucose (FPG) should be determined separately among patients actively treated with antidiabetic medication and among those solely treated with non-pharmacological therapy, suggested a recent study. Amongst patients treated with an antidiabetic medications, FBG levels showed J-shaped associations with the risks of major cardiovascular disease (CVD) events and all-cause... Read more
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    11 Nov, 2019
    A correlation between outdoor particulate matter 2.5 (PM2.5) and prevalence of chronic obstructive pulmonary disease (COPD) was demonstrated by a recent meta-analysis (odds ratio: 2.32). The heterogeneity among selected studies was significant and was mainly caused by the age of the participants (>60 or <60 years). High PM2.5 concentration should be needed in further research of the... Read more
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    11 Nov, 2019
    A recent study demonstrated with quantitative and objective evidences that better quality, longer duration, and greater consistency of sleep have robust associations with better academic performance in college. Till date several studies have reported a link between sleep and cognitive function, but none of the studies have quantitatively evaluated the association between sleep and academic... Read more
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    11 Nov, 2019
    Complications associated with long-term blood transfusions have a major impact on the quality of life of beta-thalassemia major (β-TM) patients. A recent study that stratified the risk of various severe complications in this patient subgroup revealed that in older children (≥ 5years), hepatic iron overload may be associated with a low serum concentration of 25-hydroxy vitamin D3... Read more
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    08 Nov, 2019
    Adalimumab (ADA), a monoclonal antibody targeting tumor necrosis factor-alpha, is approved for the treatment of Hidradenitis suppurativa (HS). However, the effect of weekly adalimumab (ADAew) on HS flares have not been studied. Recently researchers studied the impact of disease flare on health-related quality of life (HRQOL) in moderate-to-severe HS patients and effect of ADAew on disease flare... Read more
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    08 Nov, 2019
    Atopic dermatitis (AD) has been found to be associated with a variety of other immune-mediated diseases, including those with an autoimmune basis. Recently a cross-sectional observational study evaluated the potential association between AD and celiac disease (CD) in a broad community-based population. Researchers noted a significant association between AD and CD. Patients with AD had 60% higher... Read more
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    08 Nov, 2019
    A first-of-its-kind study evaluated the neurohormonal profile across the various ejection fraction (EF) categories of heart failure (HF) patients. While patients with HF and preserved ejection fraction (HFpEF) and HF with mid-range EF (HFmrEF) exhibited neurohormonal activation, no such activation was evident in patients with HF and reduced ejection fraction (HFrEF). Neurohormonal... Read more
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    08 Nov, 2019
    Using the electronic diaries that the patients had maintained to note stress reduction for epilepsy, researchers evaluated various factors associated with successful seizure self-prediction by patients. Self-prediction of seizures by an epilepsy patient may be associated with seizure occurrence within 24 hours, noted researchers.  A systematic increase in the odds of developing a seizure was... Read more
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    08 Nov, 2019
    A recent study revealed that although the incidence of acute malnutrition amongst children older than six months was high in rural eastern India, case fatality following severe acute malnutrition (SAM) was much lower (1.2%) than the 10%-20% estimated by the World Health Organization (WHO). Prioritizing prevention through known health, nutrition, and multisectoral interventions... Read more
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    08 Nov, 2019
    A recent systematic review and meta-analysis compared the risk of cardiorespiratory outcomes associated with inhaled corticosteroids (ICS) and/or bronchodilator-based therapies in patients with asthma-chronic obstructive pulmonary disease (COPD) overlap. The findings demonstrated that long-acting beta2-agonist (LABA) was associated with decreased risk of myocardial infarction and the combination... Read more
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    08 Nov, 2019
    The diagnosis of hypertrophic cardiomyopathy (HCM) is often delayed significantly (on average by six years) in females as compared with males, despite frequent flow obstruction in them, claimed a recent large-scale study. The study however did not demonstrate any higher incidence of heart failure (HF) mortality, arrhythmic sudden death, or other disease-related complications in females vs. males... Read more
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    05 Nov, 2019
    Insufficient response to aspirin treatment should be regarded as risk factor for ischemic events in coronary artery disease (CAD) patients, stated a recent study. According to the findings, CAD patients with enhanced platelet reactivity while on aspirin treatment had a higher risk for major adverse cardiac and cerebrovascular events (MACCE), death, and non-ST-segment... Read more
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    05 Nov, 2019
    In patients with multiple hospitalizations, those with diabetes and having higher glycosylated haemoglobin (HbA1c) levels had a higher risk of adverse renal outcomes, reported a recent study. Considering the high risk of relatively rapid renal function deterioration, structured preventive interventions are warranted in diabetes patients, irrespective of their glycemic control, concluded the... Read more