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    21 Aug, 2019
    Although it is known that both, chronic kidney disease (CKD) and end-stage renal disease (ESRD) increase the risk of death in patients with deteriorated health-related quality of life (HRQOL), the impact of HRQOL on CKD progression has not been examined thoroughly till date. A recent study elucidating this impact revealed that individuals with impaired mental health progressed to... Read more
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    21 Aug, 2019
    A recent study focused on understanding temporal trends in cardiovascular disease (CVD) risk factors in youth with recently diagnosed type-1 diabetes (T1D) and type-2 diabetes (T2D). The study demonstrated the prevalence of ≥2 CVD risk factors to be almost 8-10 folds higher in youth with T2D as against those with T1D. A greater proportion of youths with T2D also had high waist circumference (... Read more
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    21 Aug, 2019
    Early years of Soft contact lens (CL) wear are associated with increased expression of matrix metalloproteinase (MMP)-9 relative to the tissue inhibitor of MMPs-1 (TIMP-1). These findings from a recent study suggest of low-level inflammation during the early phase of CL wear. This study aimed at determining the association between levels of MMP-9, a common marker of inflammation in tears, and... Read more
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    21 Aug, 2019
    Chronic sphenoid rhinosinusitis was found to be associated with community acquired pneumonia (CAP) as per the findings of a retrospective chart review. Patients with chronic rhinosinusitis (CRS) presenting with partial/complete opacification of the sphenoid sinus were at a higher risk of developing pneumonia, added the researchers. This study was conducted to elucidate the association between... Read more
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    20 Aug, 2019
    A crossover non-inferiority clinical trial demonstrated similar improvements in inspiratory capacity (IC), forced expiratory volume in 1 sec (FEV1) and forced vital capacity (FVC) during the first 24 hours with indacaterol (IND) and tiotropium (TIO) in women with chronic obstructive pulmonary disease (COPD) associated with biomass (BE-COPD). The researchers of the trial suggested that both the... Read more
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    20 Aug, 2019
    A recent study determined the influence of ocular Demodex colonization on the Schirmer test scores and Ocular Surface Disease Index (OSDI) questionnaire values in individuals with newly diagnosed dry eye disease (DED). According to the findings, the newly diagnosed DED patients with Demodex colonization had lower average Schirmer test scores, higher OSDI scores, and higher age. Importantly, the... Read more
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    20 Aug, 2019
    Appendicitis is one of the most common diseases requiring surgery in children. Computed tomography (CT) scans provide useful diagnostic information for a variety of medical conditions. However, the increased risk of cancer from ionizing radiation exposure has led to a movement to decrease unnecessary CT scans in the pediatric population.  In a recent retrospective observational study,... Read more
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    19 Aug, 2019
    Individuals with higher 24-hour and night-time blood pressure (BP) are burdened with an increased risk of death and composite of cardiovascular (CV) events, reported a recent study.  Researchers suggested that 24-hour and night-time BP may be considered as optimal measurements for estimating the CV risk associated with BP. The robust association between BP and overall mortality and CV-... Read more
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    19 Aug, 2019
    Results of a recent study reported that height of fever was significantly associated with the risk of serious bacterial infections (SBI) in febrile infants admitted to pediatric emergency departments (EDs). On the contrary, location where fever was documented and duration of fever were not reliably associated with the risk of SBI.  Pediatric ED frequently has patients admitted for fever,... Read more
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    19 Aug, 2019
    Prediabetics have a significantly higher prevalence of non-alcoholic fatty liver disease (NAFLD) as compared to their normoglycemic counterparts, reported a recent Indian study. Higher waist circumference (WC) and gamma glutamyl transpeptidase (GGT) were the best predictors of NAFLD in prediabetes patients. The prevalence of NAFLD in patients with diabetes has been determined to some extent, but... Read more
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    19 Aug, 2019
    Invasive fungal infection (IFI) after liver transplant (LTx) is associated with extensive morbidity and mortality. It is well established that prophylaxis reduces rates of fungal infection but qualifying criteria, drug of choice and regimen are unclear. A recent observational cohort study of adult LTx recipients assessed the impact of a risk factor based fungal prophylaxis protocol (FPP) after... Read more
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    19 Aug, 2019
    Treatment of depression and anxiety in cancer with antidepressants (AD) is shown to be effective however, the link between AD adherence and mortality is unclear. A recent 4‐year historical prospective cohort study of cancer patients was conducted to assess the association between adherence to AD and all‐cause mortality in a population‐based cohort of patients with cancer. The study demonstrated... Read more
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    19 Aug, 2019
    Mishandling of inhalers was found to very common in the Portuguese cohort, according to a study that assessed the inhalation technique in stable chronic obstructive pulmonary disease (COPD) outpatients. The primary cause of the misuse of inhalation device (ID) was the failure of inhalation maneuver, which was neither associated to multiple inhalers’ use nor to patient’s preference,... Read more
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    16 Aug, 2019
    A large national cohort study revealed that infants born preterm and early-term were burdened with an increased risk of ischemic disease (IHD) in adulthood, as compared to those born full-term. The risk of IHD can be reduced in these individuals by early evaluation and preventive measures, reported the researchers. Studies in past have linked preterm birth and increased risk of hypertension and... Read more
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    16 Aug, 2019
    Women with laparoscopically confirmed endometriosis were at a higher risk of several adverse outcomes, such as, pregnancy loss, gestational diabetes (GDM), hypertensive disorders of pregnancy, preterm birth and low birth weight. The researchers of the Nurses’ Health Study II, a cohort study, suggested that elucidating mechanisms of association and potential biological pathways for... Read more