• 0
    14 Jun, 2019
    Obesity-associated type 2 diabetes mellitus (T2DM) has been effectively treated with bariatric surgery such as laparoscopic sleeve gastrectomy with high reported rates of postoperative resolution of T2DM. A recent retrospective study evaluated the effects of laparoscopic sleeve gastrectomy on glucose tolerance in Japanese obese patients with T2DM, and factors that influence diabetes remission... Read more
  • 0
    14 Jun, 2019
    Schizophrenia, a neurodevelopmental disorder, is associated with cognitive impairment that may become evident during childhood. A recent study identified specific social and family factors that influenced cognition in schizophrenia patients. Schizophrenia patients predisposed to cognitive decline faced lack of parental involvement and family breakdown and hardship along with lower... Read more
  • 0
    14 Jun, 2019
    A recent study that compared the prognosis of patients with pediatric-onset MS (POMS) and adult-onset MS (AOMS), revealed that both patient subgroups followed a distinctive clinical course. Although the POMS cases had a slower disability progression than the AOMS cases, they reached disability milestones at a significantly younger age. POMS patients with primary progressive disease, active early... Read more
  • 0
    14 Jun, 2019
    The surgery for periprosthetic femoral fracture (PFF) with revision of the femoral component can be very demanding technically. It is associated with a high rate of complications and reoperations. Direct anterior approach (DAA) has become the standard surgical approach for primary THA and the number of revisions done through this interval is increasing. Therefore, can DAA interval be expanded to... Read more
  • 0
    14 Jun, 2019
    Tenofovir alafenamide (TAF)-containing regimens have demonstrated high efficacy and favorable changes in renal biomarkers compared to a variety of unboosted and ritonavir (RTV)- or cobicistat (COBI)-boosted tenofovir disoproxil fumarate (TDF) containing regimens. However, the comparative incidence of clinically significant renal events is unknown. A recent large integrated analysis of people... Read more
  • 0
    14 Jun, 2019
    Narrowband ultraviolet B (nbUVB) phototherapy is the preferred psoriasis treatment. However, very few studies have measured the impact of nbUVB phototherapy on patient-reported measures of health-related quality of life (HRQoL) in psoriasis patients. A recent randomized placebo-controlled study evaluated the impact of both adalimumab and phototherapy compared to each other and... Read more
  • 0
    14 Jun, 2019
    Superficial dermatophytosis commonly called tinea infection includes superficial fungal infection of the skin, hair, and nail. Trichophyton rubrum has been attributed to be the most common causative dermatophyte in India. A recent study assessed the quality of life (QoL) of Indian patients suffering from superficial dermatophytosis. The results of this cross-sectional observational study showed... Read more
  • 0
    14 Jun, 2019
    Beta (β)-blockers may reduce the risk of death in patients with chronic heart failure (CHF) and atrial fibrillation (AF), stated a recent meta-analysis. A significant decrease in all-cause mortality in this subgroup of patients treated with β blockers was evident only in observational studies but not in the randomized controlled trials (RCTs). Beta-blockers did not cut down the rate of... Read more
  • 0
    13 Jun, 2019
    This was the first ever study that assessed the relationship between daily allergy symptoms and ragweed pollen concentration in European children. The lag effects on symptoms and pollen thresholds resulting in the occurrence of symptoms were evaluated. This study highlighted how different symptoms responded to the varying ragweed pollen concentrations over different time periods. The symptoms... Read more
  • 0
    13 Jun, 2019
    Vildagliptin is widely used for the treatment of type-2 diabetes mellitus () but specific requirements on cardiovascular (CV) safety assessment, issued by the US FDA has been a major concern. A recent study providing real-world data has revealed that vildagliptin did not increase the risk of CV death, nonfatal myocardial infarction (MI), nonfatal stroke, and hospitalization for heart failure... Read more
  • 0
    13 Jun, 2019
    The global prevalence of chronic kidney disease (CKD) among people living with HIV (PLHIV) is estimated at 6.4%. Use of antiretroviral treatment (ART) has decreased the prevalence of HIV-associated nephropathy (HIVAN), however, there still remains the nearly 4-fold increased risk of kidney disease, including CKD, in the people living with HIV (PLHIV) compared with the general population. A recent... Read more
  • 0
    13 Jun, 2019
    An Indian case-control study demonstrated 6-times higher prevalence of colistin resistance in Klebsiella pneumoniae isolates than Escherichia coli in urine samples of infected patients. The research team added that the emergence of resistant organisms has increased the morbidity in infected patients. The emergence of multi-drug resistant (MDR) gram-negative infections has resulted in high... Read more
  • 0
    13 Jun, 2019
    Patients suffering with Staphylococcus. aureus bacteremia have a distinctly high risk of diabetes for up to five years as compared to those without the infection, stated a recent study. Moreover, the incidence of diabetes with complications was five-fold higher and that of diabetes without complications was two-fold higher in S. aureus infected patients as compared to controls. Researchers... Read more
  • 0
    12 Jun, 2019
    A recent study demonstrated a similar incidence of thromboembolic event and bleeding complications with antiplatelet therapy (APT) and oral anticoagulation (OAC) in non-valvular atrial fibrillation (AF) patients undergoing left atrial appendage closure (LAAC) with WATCHMAN device, albeit a higher incidence of device-related thrombosis (DRT) as compared to OAC.. Researchers believe that APT might... Read more
  • 4
    11 Jun, 2019
    Upper urinary tract infection (UT), a common disease in children increases the risk for renal scarring with subsequent complications such as hypertension, proteinuria, and progressive renal failure. Nevertheless, the predictive biomarkers of renal scarring in children with upper UTI have still not been determined. A recent study hinted that serum soluble ST2 levels on admission could serve as a... Read more