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    21 Jun, 2018
    Obstructive sleep apnoea (OSA) is strongly correlated with obesity but data of bariatric surgery efficacy in resolution of OSA resolution are inconclusive. A recent study determined the rate of resolution or improvement of OSA in patients who underwent bariatric procedures. Significant improvements in OSA were reported after bariatric surgery, 55.3% of patients had resolution or improvement in... Read more
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    21 Jun, 2018
    Children with pulmonary arterial hypertension (PAH) have a lower RV end-systolic base/apex (RVES b/a) ratio than age- and gender-matched healthy children, stated a recent European study. The RVES b/a ratio was inversely associated with both echocardiographic and hemodynamic indicators of increased RV pressure afterload, and with NYHA functional class (FC). The RVES b/a ratio might be useful in... Read more
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    21 Jun, 2018
    Full-endoscopic (FE) or microendoscopic (MI) are minimally invasive surgery techniques for posterior cervical foraminotomy (PCF). In a recent study, researchers analyzed complications rates associated with FE-PCF and MI-PCF. The study showed that both FE-PCF and MI-PCF were relatively safe treatment for cervical radiculopathy. Researchers found no significant difference between the two techniques... Read more
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    20 Jun, 2018
    Elderly hypertensive patients administered single-pill fixed dose combination (FDC) rather than multipill regimen have a marked improvement in medication adherence along with better composite clinical outcomes, reported a recently published study. A single pill FDC rather than multipill regimen thus provides a potentially low-cost intervention that can substantially reduce the global burden of... Read more
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    20 Jun, 2018
    A recent longitudinal study that included over 8000 individuals confirmed that mid-life rather than late-life elevations of systolic blood pressure (SBP) were associated with increased risk of dementia. According to the findings, individuals having SBP ≥130 mmHg at age of 50 rather than at the age of 70 years were burdened with an increased risk of dementia. The fact that the presence of... Read more
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    20 Jun, 2018
    Consumptions of ultra-processed products and incidence of asthma are common during adolescence. Yet, the epidemiological evidence with regards to their association is undetermined till date. A recent Brazilian study demonstrated a positive association between the consumption of ultra-processed products and the presence of asthma and ... Read more
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    20 Jun, 2018
    The efficacy and safety of retrograde intrarenal surgery (RIRS) in treatment of multicalyceal and multiple renal stones was higher than percutaneous nephrolithotomy (PNL), concluded a new study which compared both the procedures. RIRS resulted in higher stone-free rate with lower rates of hospitalization and complications. The patients who underwent surgery for multiple stones in different... Read more
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    20 Jun, 2018
    High sustained virologic response rates (SVR) were attained in genotype (GT) 2 and GT3 HCV-infected patients treated with daclatasvir plus sofosbuvir with or without ribavirin (DAC+SOF±RBV) and velpatasvir/sofosbuvir with or without ribavirin (VEL/SOF±RBV). A recent real-world clinical study also added that the patients who received prior treatment or had cirrhosis, decompensated... Read more
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    19 Jun, 2018
    CAPTURE, an international retrospective study demonstrated that switching the patients to riociguat from another PH-targeted medical therapy was feasible in real-world clinical practice. Changing over to a new drug in some patients with PAH and CTEPH due to insufficient clinical response or safety reasons seems to be an appropriate option. CAPTURE, a multicenter study, assessed the feasibility of... Read more
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    19 Jun, 2018
    DARWIN-T2D, a large retrospective real-world study revealed that addition of dipeptidyl peptidase-4 inhibitor (DPP4i) rather than gliclazide [sulfonylurea (SUs)] to the ongoing glucose lowering regimen yielded superior glycemic control in type-2 diabetes mellitus (T2DM) patients. DPP4i and SUs comprise the most popular second-line therapies for T2DM. Yet, the real-world data comparing the... Read more
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    19 Jun, 2018
    Children born preterm are at an increased risk of asthma in early childhood. A team of researchers recently investigated whether wheezing trajectories across childhood were associated with preterm birth.  According to the findings, children with a gestational age of <37 weeks at birth, were burdened with an increased risk of wheezing characterised as 'early-remittent' or... Read more
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    19 Jun, 2018
    A recent Cochrane systematic review of studies inferred that treatment with alpha-blockers might increase the clearance of ureteral stones. However, the study also stated that alpha-blockers might be associated with a slight increase in the risk of major adverse events. Treatment with alpha-blockers might be more effective in larger stones with size >5 mm as compared to smaller stones with a... Read more
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    19 Jun, 2018
    A recent study that determined the impact of blinking on tear film parameters, ocular surface characteristics, and dry eye symptomology revealed that individuals with incomplete blinking have a two-fold increased risk of dry eye disease (DED). The study further hinted that greater levels of meibomian gland dropout, poorer expressed meibum quality and tear film lipid layer thickness hike the risk... Read more
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    19 Jun, 2018
    The incidence of liver-related complications, hepatocellular carcinoma (HCC), death and hepatitis C virus (HCV) relapse is very low in the first 144 weeks of follow-up in HCV-infected patients with F2 or F3 fibrosis who achieve sustained virologic response (SVR) with direct-acting antiviral (DAA) therapy, noted a new study. The authors of the study recommended early treatment of HCV infection.... Read more
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    18 Jun, 2018
    RESPECT trial is a randomized control trial investigating benefits of trastuzumab (H) monotherapy as an adjuvant treatment compared to the standard combination treatment with chemotherapy (CT) in elderly women with human epidermal growth factor receptor type-2 (HER2)-positive breast cancer (BC) patients (pts). The recent data from this study was presented in ASCO 2018 conference. Based on hazards... Read more