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    22 Apr, 2020
    Dental implant placement in oral cancer patients results in improved oral function post oncological treatment. Recently a study analysed the performance of implants placed immediately after teeth extraction in the mandible during ablative surgery or preceding primary radiotherapy and describe oral function and denture satisfaction after immediate implant placement in patients with head and neck... Read more
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    22 Apr, 2020
    Amongst type-2 diabetes mellitus (T2DM) treated with metformin, those receiving novel glucose lowering drugs as second-line therapy had a lower risk of cardiovascular disease (CVD) and adverse event as compared to those receiving sulfonylurea. The benefits of novel glucose lowering agents such as sodium glucose cotransporter-2 inhibitor (SGLT-2i), dipeptidyl peptidase-4 inhibitor (DPP-4i) and... Read more
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    22 Apr, 2020
    Endoscopic subureteral injection of polyacrylate/polyalcohol copolymer for the treatment of vesico-ureteric reflux (VUR) was effective and safe in patients presenting with recurrent urinary tract infections (UTIs) after kidney transplantation. Lack of an effective antireflux mechanism in most techniques used during kidney transplantation is the common cause of UTIs. Subureteral injection of... Read more
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    22 Apr, 2020
    A recent randomized cross-over study demonstrated the bioequivalence of three oral formulations developed during the clinical development of pediatric bilastine. Additionally, all the formulations were well tolerated by the healthy subjects. The authors of the study therefore recommended the use of these formulations in children with allergic rhinoconjunctivitis and urticaria. This study... Read more
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    21 Apr, 2020
    Dry eye disease (DED) is a chronic, progressive ocular surface disorder that affects multiple aspects of daily life; hence the more comprehensive approach is needed to estimate its overall burden. Recently, a cross-sectional survey evaluated vision-related quality of life (QoL), ocular symptoms, general health status, and work productivity in individuals with and without DED residing in the... Read more
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    21 Apr, 2020
    There has been increasing evidence regarding hyperuricemia as an independent risk factor for many cardiovascular diseases and psoriasis. A recent cross-sectional case-control study investigated the association between hyperuricemia and AGA in men. Researchers noted a significant relationship between hyperuricemia and AGA in men. The prevalence of hyperuricemia was significantly higher in patients... Read more
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    21 Apr, 2020
    Mucormycosis although rare, is an emerging life-threatening fungal disease, which currently has limited treatment options. Isavuconazole, a new triazole appears promising in adults for primary and salvage treatment of mucormycosis. Data of isavuconazole in pediatric patients is however rare. This small-scale study strengthens the role of isavuconazole as salvage... Read more
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    21 Apr, 2020
    Type-2 diabetes mellitus (T2DM) with preoperative metformin exposure have a lower risk of 90-day mortality after a major surgery as compared with their counterparts without preoperative metformin exposure, stated a recent study. Moreover, patients with preoperative metformin prescription also had lower 30-day and 90-day rehospitalization as against those without preoperative metformin... Read more
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    21 Apr, 2020
    The national and international guidelines recommend systemic antibiotic prophylaxis (AP) within a surgical bundle to prevent surgical site infections (SSI) among patients undergoing colorectal surgeries. However, compliance with AP recommendations remains low. A recent retrospective cohort study assessed compliance with recommendations and effectiveness of AP for the prevention of SSI in children... Read more
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    21 Apr, 2020
    A recent large-scale, real-world study stated that the loop diuretic (LD) dose remained unchanged in majority (76%) of the chronic heart failure (HF) outpatients. The medication was down-titrated in 8.3%. An increase in LD dose was associated with worse outcomes; in contrast, decrease in LD dose was associated with a trend towards better outcomes vs. the no-... Read more
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    20 Apr, 2020
    Recently, The National Comprehensive Cancer Network (NCCN) issued guidelines for managing patients specifically with recurrent/stage IV breast cancer. These guidelines are developed by the NCCN Breast Cancer Panel and discusses the appropriate therapeutic strategy for patients with recurrent/stage IV disease. Completed guidelines are available on: https://www.nccn.org/professionals/physician_gls... Read more
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    20 Apr, 2020
    Preschool children with an overweight or obese range body mass index (BMI) are at an increased risk of upper and lower limb fractures in childhood as compared with their normal weight counterparts. These are the findings of a recent large-scale study that was conducted preschool children in Spain. Researchers determined if an overweight or obese range BMI at time of beginning... Read more
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    20 Apr, 2020
    Infliximab (IFX) is efficacious in patients with psoriasis as assessed in several randomized controlled trials; however, long-term drug survival data of IFX in real-life settings is limited. A recent multicenter retrospective study investigated psoriasis patients treated with IFX for longer than six years. Researchers found that at the end of the study, 70% of patients were still on IFX at 4... Read more
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    17 Apr, 2020
    Surgical site Infections (SSTIs) are the most commonly occurring infections. Complex skin and soft tissue infections (cSSTIs) are the more severe type of SSTI and often associated with high medical costs and a high mortality rate.  In a recent retrospective study, researchers compared the efficacy and safety of standard-dose (SD) daptomycin with those of high-dose (HD) daptomycin in... Read more
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    17 Apr, 2020
    Voriconazole has demonstrated inhibition of ergosterol synthesis in various acanthamoeba species. Recently, the clinical outcome of supplemental topical voriconazole treatment in patients with acanthamoeba keratitis (AK) was evaluated. The results of this study showed that infection was resolved in all eyes. Best-corrected visual acuity improved during therapy. The study concluded that... Read more