• 0
    13 Apr, 2020
    Short-term intensive insulin therapy can improve both beta-cell and alpha-cell function in newly diagnosed type-2 diabetes mellitus (T2DM) patients, reported a recent study. This may be beneficial for the patient allowing better, long-term metabolic control with minimal oral hypoglycemic agents (OHA), according to the investigating team.  It is... Read more
  • 0
    13 Apr, 2020
    Allergen‐specific subcutaneous immunotherapy (SCIT) for Japanese cedar pollinosis resulted in a decrease in the number of metachromatic cells in nasal swabs in the preseason. Furthermore, SCIT inhibited increases in the number of metachromatic cells and eosinophils in season, were the findings of a recent study, which assessed the mechanisms underlying the efficacy of SCIT. Since there is no... Read more
  • 0
    10 Apr, 2020
    A recent study demonstrated that ticagrelor monotherapy as against ticagrelor plus aspirin consistently reduced the risk of clinically relevant bleeding without any increase in the risk of ischemic events over a period of one year in patients with diabetes mellitus (DM) who had received dual antiplatelet therapy (DAPT) for three months following percutaneous coronary intervention (PCI). The... Read more
  • 5
    10 Apr, 2020
    Pityriasis versicolor (PV) is a chronic superficial fungal infection caused by Malassezia species. It is most prevalent among young and middle-aged persons who live in regions with high humidity and temperatures. Treatment of this condition is mainly focused on synthetic antifungal drugs e.g. ketoconazole. A recent randomized double-blinded study compared the clinical outcome of 0.1% adapalene... Read more
  • 0
    10 Apr, 2020
    A recent study that determined the association between age and depressive symptomatology before and during antidepressant treatment revealed, that the clinical presentation of depression varied substantially with age in patients with major depressive disorder (MDD).  While some of these differences persisted throughout the treatment, some of them disappeared. Personalized antidepressant... Read more
  • 0
    10 Apr, 2020
    The diagnostic accuracy of detecting prostate cancer significantly improved with the incorporation of multiparametric magnetic resonance/transrectal ultrasound fusion (MRI/TRUS fusion) biopsy as compared to systematic biopsy, particularly for anterior lesions. This study compared the efficacy of MRI/TRUS fusion biopsy with systematic biopsy and assessed its association with PI-RADS v2 categories... Read more
  • 0
    09 Apr, 2020
    The novel feeding strategy of oropharyngeal colostrum (OC) is known to prevent complications of prematurity. A recent meta-analysis stated that OC significantly reduced the occurrence of ventilator-associated pneumonia (VAP) and necrotizing enterocolitis (NEC) in very low birth weight (VLBW) infants. Researchers recommend the routine use of OC in VLBW infants to prevent... Read more
  • 0
    09 Apr, 2020
    LATITUDE is a randomized, double-blind, active-controlled study that compared efficacy and safety of abiraterone acetate plus low-dose prednisone (AAP) + androgen deprivation therapy (ADT), with placebo for abiraterone acetate and prednisone (PBO) + ADT in men with high-risk metastatic castration-sensitive prostate cancer (mCSPC). The study demonstrated that significantly longer overall survival... Read more
  • 0
    09 Apr, 2020
    A recent pooled analysis of 13 case-control studies demonstrated a significant reduction in the risk of ovarian cancer including the high-grade serous subtype, the most lethal type of ovarian cancer with breastfeeding. A further decrease in risk was associated with longer breastfeeding duration and shorter time since the last breastfeeding episode. The researchers added that breastfeeding might... Read more
  • 0
    08 Apr, 2020
    A recent study that evaluated the susceptibility rates of almost 20,000 gram-negative organisms across 41 countries demonstrated a wide variation among geographic regions and were generally lowest in eastern Europe and the Mediterranean region (E-EUR). The researchers highlighted that cefoperazone-sulbactam was among the most active compounds in vitro against Enterobacterales,... Read more
  • 0
    08 Apr, 2020
    Efficacy of intracameral moxifloxacin prophylaxis in reducing the endophthalmitis rate after cataract surgery has been demonstrated in retrospective and randomized controlled studies. Recently a randomized, prospective, masked, paired-eye clinical study was conducted in India to compare the central corneal endothelial cell loss (ECL) 3 months postoperatively for a 250-µg vs 500 µg... Read more
  • 0
    08 Apr, 2020
    A novel study applied the 5-2-1 criteria to a general cohort of Parkinson’s disease (PD) patients to ascertain its impact on their quality of life (QoL).  According to the findings, PD patients, positive for at least one of the 5-2-1 criterion had worse health-related and global-QoL as compared to the PD patients with 5-2-1 negative criteria. Overall, patients with positive 5-2-1... Read more
  • 0
    08 Apr, 2020
    Nasal irrigation (NI) with a sea-water solution in addition to regular treatment demonstrated significant symptomatic improvement in allergic rhinitis (AR). Control of allergic rhinitis and asthma test (CARAT) questionnaires and MASK/Allergy Diary could be valuable outcome tools in real-life studies, added the researchers. Clinical studies on the efficacy of NI as an adjunctive treatment for... Read more
  • 0
    07 Apr, 2020
    Treatment of acne scars with laser resurfacing has been demonstrated to be an efficient therapy option. The non-ablative 1450-nm diode laser has also been found efficient for acne vulgaris and atrophic acne scars both in light and dark-skinned patients. But very few studies have demonstrated its efficacy in the treatment of facial acne scars. Recently, a multi-centre cross-sectional study... Read more
  • 0
    07 Apr, 2020
    A recent study demonstrated that vitamin A (VA) deficiency exacerbated the core symptoms in children with autistic spectrum disorder (ASD). Furthermore, the study revealed a greater severity of core symptoms in ASD children with comorbid gastrointestinal (GI) symptoms as against those without such comorbidities. Vitamin A deficiency coupled with comorbid with GI ... Read more