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6 Jan, 26
The 2025 ACC guidance highlights critical care in cardiogenic shock by recognizing the hemodynamic impact of PEEP on ventricular function, selecting invasive ventilation when instability warrants, and applying early structured interventions during the Golden Hour to support perfusion.
6 Jan, 26
The 2025 ACC guidance outlines stage-based management in cardiogenic shock, using vasoactive therapy to support perfusion and advancing to temporary mechanical support when organ perfusion remains inadequate after medical optimization.
7 Jan, 26
Respir Med
- The study assessed whether early termination of the 6-minute walk test (6MWT) predicts poor outcomes in COPD
- Among 2,085 patients, 6.3% stopped early, showing worse lung function and higher symptom burden
- Early termination correlated with increased exacerbations, higher 3-year mortality, and prognostic value comparable to the BODE index, making it a practical marker for risk stratification.
7 Jan, 26Indian J Ophthalmol.
- A case series of 9 IA patients: 7 went to ophthalmologist for vision defects (age 58.9 y, 71% female)
- Symptoms: diplopia 57%, defective vision 43%, comorbidities in 43%
- Examination showed 3rd nerve palsy, 6th palsy (both 28.5%), RAPD/optic pallor (43%), hemianopia (14.2%); as per MRI: anterior aneurysm 100%, posterior 11%, multiple 28.5%; morphology: saccular 71.4%, fusiform 28.5%
- Early detection of IA is vital.
6 Jan, 26Eur J Clin Microbiol...
- P. aeruginosa bloodstream infections showed high risk (N=5,742). Mortality: 20.5% died within 30 days, 21.3% within 3 years, 4.6% recurred, and 53.6% survived
- Recurrence was linked to malignancy, metastatic cancer, diabetes; mortality to malignancy, CHF, dementia, renal/pulmonary disease, age
- Community-onset/genitourinary sources lowered risks. Resistance emerged but profiles largely stable.
6 Jan, 26Diabetes Res Clin Pr...
- Amongst 186,473 type 2 diabetes mellitus patients (median age 62 y; 50.9% women), 3,551 (1.9%) developed diabetic foot ulcer (DFU) & 53,118 (28.5%) died over an 8.8 y follow-up
- Frailty increased the risk of DFU & mortality, at age 60; 10 y DFU probability in women was 2.1%, 1.9%, 2.9%, & 3.2% for fit, mild, moderate, & severe frailty; in men 2.6%, 2.7%, 3.7%, 4.4%
- Frailty stratification aids DFU risk prediction.
6 Jan, 26
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