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4 Nov, 25
WHO SE Asia’s Dengue Case Management booklet guides frontline care with protocols for early detection, fluid management, and referrals. It supports primary and home care with tools like monitoring charts and outbreak strategies for resource-limited settings.
4 Nov, 25
This FIGO’s statement highlights HPV vaccination's role to eliminate cervical cancer, emphasizing early immunization, single-dose efficacy, safety, and equitable access to meet WHO’s 90% coverage target by age 15.
4 Nov, 25
BMC Pediatr.
- A high prevalence of vitamin A deficiency (VAD) was reported in pediatric sepsis vs. controls (61.7% vs. 20%; P<0.001)
- VAD correlated with higher PRISM scores, greater sepsis severity, and longer pediatric ICU stays
- Serum vitamin A levels ≤21.4 µg/dl predicted sepsis in children (AUC 0.699, P<0.001)
- VAD was frequent in non-survivors (71.4%); no correlation seen with mortality.
4 Nov, 25Open Forum Infect Di...
- In ICU patients, polymicrobial bloodstream infections were linked to similar risk of 90-day mortality versus monomicrobial ones(31.1% vs. 28.3%; not significant)
- No major differences were found in other outcomes of all-cause 30-day mortality, microbiological failure, initiation of extracorporeal membrane oxygenation, acute respiratory distress syndrome, fever or hospital stay.
3 Nov, 25Diabetes Res Clin Pr...
- 2257 T2DM patients treated with CRTd were classified as: SGLT2i monotherapy, GLP-1RAs monotherapy, & combination therapy (GLP-1RAs/SGLT2i) users
- Combination therapy showed superior CRT response (66.3%) vs SGLT2i (59.6%) & GLP-1RAs (59.2%), & lower HF hospitalizations (HHF; 15.7% vs 23.5% & 24.4%)
- Combination therapy independently predicted CRT response (HR 1.659; p=0.001) & reduced HHF (HR 0.822)
3 Nov, 25Hypertension.
- Magnesium supplementation (82.3–637 mg/day; median 365 mg) over ≥4 weeks (median 12 weeks) reduced SBP by −2.81 mmHg & DBP by −2.05 mmHg, vs placebo
- Greater effects were seen in hypertensives (−7.68/−2.96 mmHg) & hypomagnesemic individuals (−5.97/−4.75 mmHg; P<0.05)
- Large-scale studies are warranted to refine the dose-response relation between BP & magnesium intake.
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