Recent updates in endometriosis management (FOGSI-ICOG) include medical and surgical options. First-line treatments are NSAIDs, combined oral contraceptives (COCs), and progestogens (Dienogest, LNG-IUD). GnRH agonists/antagonists are second-line with add-back therapy. Aromatase inhibitors are third-line for resistant cases. Surgery is for severe or refractory cases, aiming to remove lesions while preserving function.

Nebulization therapy uses jet, ultrasonic, and mesh nebulizers based on drug formulation and patient needs. Bronchodilators, corticosteroids, mucolytics, and antimicrobials are common for ventilated patients. Jet nebulizers are ideal for prolonged treatments with unstable drugs, while ultrasonic nebulizers offer efficient aerosol delivery. Mesh nebulizers provide precise dosing. Proper cleaning is key to safety.

Diabetic patients with severe subclinical hypothyroidism (SCH) had a 6-fold higher risk of macrovascular complications, while those with moderate SCH had a 4.35-fold increase. Complications occurred in 90.5% of severe, 80.9% of moderate & 59.9% of mild SCH cases. Severe SCH was linked to peripheral artery disease (OR: 5.91) & coronary artery disease (OR: 3.26), underscoring the need for proactive TSH monitoring.

A study revealed that hypertensive patients on thiazide had a higher incidence of falls/syncope than non-users (32.2% vs. 19.5%). Risk factors included older age, longer thiazide use, metabolic alkalosis, and decreased eGFR. Electrolyte imbalance, acute kidney injury, and chronic kidney disease were more prevalent in this group, underscoring the need for close monitoring and individualized treatment.

Sarcopenic obesity (SO) worsened outcomes in diabetic patients with heart failure with reduced ejection fraction (HFrEF). Those with SO had greater left ventricular (LV) enlargement, dysfunction, and mass, along with a threefold increased risk of unfavourable events (HR: 3.03) compared to those without sarcopenia or obesity. These findings underscore the need for targeted interventions in this high-risk group.

A novel predictive model may aid clinicians in assessing the risk of chronic pain following calcaneal fracture surgery. Research identified key factors, including BMI, operative duration, surgical approach, and Böhler angle, as independent predictors. The model demonstrated strong predictive performance (AUC: 0.691), enabling risk assessments and targeted interventions to improve post-surgical outcomes.