DETeCD-ADRD guideline provides a structured, multi-tiered approach for diagnosing and evaluating suspected Alzheimer’s Disease and Related Dementias (ADRD) in primary care, emphasizing patient-centered communication, validated cognitive assessments, and individualized laboratory and imaging tests. It also outlines a stepwise diagnostic disclosure process, ensuring patients and caregivers receive clear information abo...

A long-spanning study confirmed that one-standard deviation rise in high-sensitivity troponin T (hs-troponin T) levels in individuals with metabolic dysfunction-associated liver disease (MASLD) was associated with a 29% increase in all-cause mortality (HR: 1.29) and a 44% rise in cardiovascular mortality (HR: 1.44), despite no prior cardiovascular disease. Similar findings were observed for hs-troponin I.

WHO’s first report on fungal infections highlights critical shortages in antifungal drugs & diagnostics amid rising resistance, especially in low- & middle-income countries & immunocompromised individuals. With mortality rates reaching 88% for some infections, only four new drugs have been approved in a decade and few are in the late-stage trials. WHO urges stronger surveillance, R&D investments and rapid diagnostics...

Higher serum calcium levels may raise rosacea risk, while potassium could offer protection, a genetic study suggests. Mendelian randomization analysis found elevated calcium doubled the odds of rosacea (OR: 2.27), whereas higher serum potassium levels slashed risk by 64% (OR: 0.36). These findings highlight a potential role of micronutrients in rosacea development.

High adherence (score 6-8) to the American Cancer Society (ACS) lifestyle guidelines post-cancer diagnosis lowered all-cause mortality by 24% (HR: 0.76), cardiovascular mortality by 33% (HR: 0.67) and cancer-specific mortality by 21% (HR: 0.79) compared to low adherence (scoring 0-3), a 15-year follow-up study found. Survivors who improved their score from low also had reduced all-cause mortality.