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31 Dec, 25
AOCCN 2025
Key session presented at the 17th Asian Oceanian Child Neurology Congress, 2025, on developmental and behavioural disorders.
31 Dec, 25
This is the first-of-its kind clinical guidance from the WHO on the pharmacological treatment of obesity in adults. The guidelines focus on the use of long-term GLP-1 therapies combined with intensive behavioral therapy to maximize and sustain benefits in obese.
30 Dec, 25Am J Obstet Gynecol.
- 40 RCTs (n≈5,408) included
- Diuretics (7 trials, n=1113) improved BP control with antihypertensives but not alone
- Antihypertensive comparisons (12 trials, n=961) showed enalapril/amlodipine more effective than nifedipine; diltiazem lowered BP vs. nifedipine in severe cases (n=403)
- BP self-monitoring/lifestyle change (9 trials, n=1263) reduced BP at 8 months postpartum.
29 Dec, 25Endocr Pract.
- A study of 124 youths (mean age 12.9 y, T1DM duration 6.0 y; HbA1c 8.1%, glucose TIR 49%) showed mean BMD z-score –0.2 (lower than pediatric norms)
- BMD z-score correlated with BMI z-score (r=0.32, p=0.0002), TIR (r=0.24, p=0.007), 25OHD (r=0.22, p=0.01), & high-impact activity EE (r=0.02, p=0.03)
- 51% of the study population was vit D deficient, vit D deficiency lowered BMD (Δ0.7); activity raised BMD (Δ0.3)
26 Dec, 25Diabetes Obes Metab.
- A meta-analysis of 19 studies (n=1,371,533) found CKD prevalence in T1DM at 22.3%; highest in Americas (27%), lowest in Europe (19.4%)
- Prevalence was higher in adults vs adolescents (20.5% vs 10.5%); with duration ≥10 y vs <10 y (21.8% vs 16.4%); HbA1c ≥8% vs <8% (27.7% vs 17.9%)
- Meta-regression confirmed the link between higher HbA1c & CKD prevalence
- Regular screening is essential to mitigate CKD burden in T1DM.
24 Dec, 25Int J Antimicrob Age...
- Global meta-analysis (2019-23) of 44 studies across 16 countries; largest number of studies were collected from India (n = 9)
- Carbapenem-resistant E. coli prevalence found to be 7%
- NDM was the most common carbapenemase, followed by OXA, KPC, VIM, and IMP.
- Findings highlighted significant global variability. Highest.
12 Dec, 25
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