Telmisartan Significantly Improves Insulin Sensitivity in Hypertensive Obese Patients
Telmisartan vs Olmesartan in Hypertensive Obese Patients
12 Dec, 10
Telmisartan vs Olmesartan in Hypertensive Obese Patients
Aim
To evaluate the effect of treatment with Telmisartan Vs Olmesartan in hypertensive obese and overweight patients.
Study Patients
Overweight and obese patients with mild to moderate hypertension (N=65)
Study Groups
Telmisartan 80 mg/day Vs Olmesartan 40 mg/day
Study Duration
3 months
Efficacy Endpoints
Measurement of insulin, glucose, HOMA and leptin levels
Results
Treatment with Telmisartan for 3 months showed a significant improvement in glycemic parameteres and leptin levels, unlike olmesartan.
Conclusion
Unlike olmesartan telmisartan significantly improves insulin, glucose, HOMA and leptin levels in hypertensive diabetic patients compared to olmesartan.
Nutr Hosp 2010; 25: 275-279